Emergency departments are often the first point of care after an opioid overdose — and one of the most important opportunities to prevent the next one. The Virginia Naloxone Project helps hospitals put naloxone directly into the hands of patients before they leave the ED.
More than a life-saving medication, naloxone represents an opportunity to connect with patients, communicate that their lives matter, and provide a tangible tool that can help keep them safe and alive.
Patients treated in the emergency department after a nonfatal opioid overdose face an elevated risk of death in the months that follow. The Virginia Naloxone Project addresses that risk by helping ED teams provide free naloxone kits, basic education and recovery resource information at discharge.
Emergency physicians and nurses meet patients during moments of immediate risk, vulnerability and potential openness to support. That makes the ED a powerful place for life-saving intervention.
Naloxone kits include the medication, basic instructions and referral information for recovery services, supported by a brief explanation from a clinician.
Direct distribution removes barriers such as cost, transportation and pharmacy access while signaling compassion and reducing stigma around substance use disorder.
A 2026 study in JACEP Open argues that emergency departments should look beyond patients treated for opioid overdose alone when estimating the need for naloxone distribution. Using ED discharge data, researchers found a much broader group of patients at risk who could benefit from take-home naloxone.
Researchers estimated that U.S. emergency departments saw at least 3.87 million visits by patients at risk of opioid overdose.
By comparison, visits specifically for opioid overdose treatment represented a much smaller estimate of naloxone need.
The study estimates that about 3% of all ED visits involved patients who were at risk of overdose.
The Virginia Naloxone Project reflects what emergency medicine does every day: meet patients where they are, respond to immediate danger and create a path toward survival. For hospitals and ED teams, participation is a concrete way to reduce overdose deaths, support patients with substance use disorder and strengthen compassionate, stigma-free care.
The Virginia Naloxone Project is expanding to emergency departments across the Commonwealth, with the goal of reaching every ED in Virginia.
Get started.Get the toolkit. The Naloxone Project's Hospital & Emergency Department Implementation Toolkit includes sample policies, workflow guides, stakeholder presentations, dispensing protocols, staff training materials and patient education resources to help hospitals successfully implement take-home naloxone programs. Download it here.